Sample Paper Outline

Kristen Westergaard
Immunology Outline
2/29/08

I. Overview of the two parts of the immune system
a. Innate Immune System
i. Possessed by invertebrates and vertebrates. [19] [26]
ii. General attack to a foreign molecule
b. Adaptive Immune System
i. Supposedly only in vertebrates
ii. More specific responses to individual foreign molecules
iii. Creates memory cells that allow for a quicker response upon re-exposure to pathogen
II. Mechanisms of Innate Immunity in Invertebrates
a. Melanization [5] [36]
b. Complement cascade [1] [6] [25] [8]
c. Humoral [4] [5] [10]
i. AMPs [23] [34] [28]
ii. Clotting [15] [39] [17] [27] [37]
iii. Cytokines [9] [8] [31]
d. Cellular [4] [16] [24] [32] [33] [38]
e. Other- Antiviral responses [35] [37]
f. Interactions between mechanisms [4] [34] [36] [22]
g. Regulation of Innate Immune System [39] [11] [2] [5] [14] [20] [21] [10] [31]
III. Possible Specific Responses in Invertebrates [3] [12] [13] [5] [18] [22] [29] [30] [33]
IV. Invertebrate Immune System, Evolution, and the Adaptive Immune System of Vertebrates (Summary)

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